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Objectives.  There is a set of evidence about the adverse effects of engineered nanomaterials (ENMs) on humans and the environment. People working with nanomaterials (NMs) (in nanotechnology laboratories and workplaces) are often exposed to these materials. Following nanosafety principals can reduce exposure to ENMs. This study aimed to investigate the knowledge, attitude and practice (KAP) of Iranian researchers toward nanosafety.  Methods . This descriptive cross-sectional study was conducted via a questionnaire designed using the results of a literature review and validated by a panel of experts. After completion of questionnaires by Iranian researchers, data were analyzed using SPSS version 20.0.  Results . Investigation into the knowledge of study participants showed that 61.38% of them answered the questions correctly. Although 74.34% of the study participants had a proper attitude to nanosafety, only 27.3% of them considered ENMs to be harmful to humans and the environment. Examination of researchers’ performance in laboratories showed that 24.25% of them ‘always’ have good performance.  Conclusions . It seems that increasing awareness by teaching the principles of working safely with NMs can help to create a positive attitude toward the principles of nanosafety. Positive attitude can finally lead to the optimal performance of researchers in laboratories involved with NMs.

Nanosafety: a knowledge, attitude and practice (KAP) study among Iranian researchers working in nanotechnology laboratories