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With excellent mechanical properties and high specific surface area, mesoporous silica microspheres are widely applied in various fields. However, mesoporous silica has been relatively studied as a thin-layer chromatographic (TCL) material for preliminary separation and detection. In this study, we obtained mesoporous silica microspheres with different particle sizes and apertures by a simple synthesis method, and prepare mesoporous silica microspheres-based TCL. Excellent test results have been exhibited, the 4.5 μm mesoporous silica microspheres-based TCL exhibits better separation results in dye and fluorescent polymer separation experiments, thus expanding the application of mesoporous silica microspheres.

Preparation and Application of Novel Mesoporous Silica Microsphere-Based Thin Layer Chromatography Plate