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Olive flounder is a common surimi industry related fish species in South Korea that generates a considerable amount of solid waste. To maximize the utilization of olive flounder gut (OFG) byproducts, OFG was subjected to enzymatic hydrolysis. Antioxidant activity of the obtained hydrolysates was evaluated to investigate radical scavenging activity (RSA), and  in vitro  experiments were conducted on 2,2’-azobis(2-amidinopropane) dihydrochloride-stimulated Vero cells. Protamex hydrolysates showed a strong RSA (IC 50  value of 94.96 ± 1.60 µg/mL) with a significant reduction in oxidative stress in  in vitro  and  in vivo  zebrafish models. OFG byproducts have potential for industrial application as antioxidative agents.

journal of aquatic food product technology

Protective Effect of Fish Gut Hydrolysates from Olive Flounder ( Paralichthys olivaceus ) Surimi Byproducts Against AAPH-Induced Oxidative Stress in  In Vitro  and  In Vivo  Zebrafish Models