English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The analgesic and anti-inflammatory effects of  Grewia asiatica  leaf solvent extracts were evaluated in animal models. The methanol and ethyl acetate fractions prepared from the leaves showed potent analgesic and anti-inflammatory effects at 400 mg kg −1  and 100 mg kg −1 , respectively. Myricetin was isolated from the ethyl acetate fraction by column chromatography. Molecular docking studies with myricetin showed a desirable binding pattern of myricetin with both COX-1 and COX-2, supporting its anti-inflammatory potential. Results showed that the anti-inflammatory and analgesic effect of methanol extract of  G. asiatica  leaves may be due to COX-1 and COX-2 inhibition by myricetin.

Ameliorative Effects of Grewia asiatica Leaves in Animal Models of Pain and Inflammation