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The antioxidant activity and antibacterial efficacy of aqueous and ethanolic extracts of  Chaetomorpha linum  were tested against bacterial infection caused by  Pseudomonas aeruginosa . In vitro and in vivo studies revealed the efficacy of ethanolic extract of  C. linum  in controlling the  P. aeruginosa  infection. Gas Chromatography Mass Spectroscopy analysis of purified fractions of ethanolic extract was also performed. Ichthyotoxic bioassay of purified seaweed extracts was performed to assess its toxic effect in rohu fish and found to be nontoxic. Experimental pathogenicity of  P. aeruginosa  showed exophthalmia, reduced intake of feed, and lesions on the body. LD 50 was achieved at the 3.96 × 102 at 48 h and 4.82 × 103 at 72 h in the experimental pathogenicity. The results revealed that the ethanolic extract of  C. linum  can be used as an alternate source for controlling  P. aeruginosa  infection in  L. rohita .

journal of applied aquaculture

Antioxidant and antibacterial efficacy of  Chaetomorpha linum  and its toxicological evaluation for the prophylactic treatment against  Pseudomonas aeruginosa  infection in  Labeo rohita