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Previous studies have identified associations between affectionate communication and blood lipid levels but been limited by small, homogenous samples and failed replication attempts. Moreover, no study has tested the prediction derived from affection exchange theory that stress mediates the association between affectionate behavior and health. Using secondary analyses of data from the Midlife in the United States (MIDUS) Refresher study Biomarker Project, this paper remedies these limitations by testing the prediction that stress mediates the association between kissing and serum levels of triglycerides, high-density lipoproteins, and low-density lipoproteins using a large probability sample of U.S. American adults ( N  = 863). Results indicate significant indirect effects of kissing frequency on triglycerides and high-density lipoproteins for participants who reported kissing seven or more times in the previous month.

Lipidemic Effects of Kissing are Mediated by Stress: Results from a National Probability Sample