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Efficient synthesis of dispiro[indoline-3,4'-pyrrolidine-3',2''-naphthalene]-1'',2,3'',4''-tetraone ( 3 ) and spiro[imidazole-4,2'-naphthalene]-1',3',4'-trione derivatives  4  that derived from lawsone moiety as high reactive building block are confirmed  via  1,3-dipolar cycloaddition of azomethine ylides generate  in situ  from benzyl amine and isatin occurred at the double bond of arylidene of lawsone upon heating and or  via  addition α,β-unsaturated ketone  2  with oxidizing agent hydrogen peroxide (H 2 O 2 ) (30%) and guanidine.HCl in one portion.

Regiochemistry in Cycloaddition Reaction to Synthesize of Some Novel Lawsone-Spiro Compounds