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A new series of 6,9-dihydrofuro[3,2- f ]quinoline-8-carbonitrile derivatives were prepared,  via  one-pot reaction of ethyl 5-aminobenzofuran-2-carboxylate, aromatic aldehydes and 3-oxo-3-phenylpropanenitrile in ethanol as a solvent at reflux. The advantages of this protocol include mild reaction conditions, easy purification, high yields, and catalyst-free approach. IR,  1 H NMR,  13 C NMR and HRMS spectras were used to identify the structures of all the synthesized compounds.

An Efficient One-Pot Synthesis of 6,9-Dihydrofuro[3,2- f ]Quinoline-8-Carbonitrile Derivatives under Catalyst-Free Conditions