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In this study, some novel pyridopyrimidines were synthesized via one-pot three-component reaction of 6-amino- N,N -dimethyluracil, 3-(1-methyl-1 H -pyrrol-2-yl)-3-oxopropanenitrile and aromatic aldehydes in DMF under reflux conditions in the presence of 1-carboxymethyl-2,3-dimethylimidazolium iodide {[cmdmim]I} as a catalyst. The present procedure shows several advantages such as short reaction times, high yields, simple work-up and use of non-expensive and nontoxic materials. All products were characterized by spectroscopic (FT-IR,  1 H and  13 C NMR) analyses.

polycyclic aromatic compounds

A Convergent One-Pot Synthesis of Novel Pyrrole-Pyridopyrimidines Hybrids Using 1-Carboxymethyl-2,3-Dimethylimidazolium Iodide {[cmdmim]I} as a Recyclable Catalyst