English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

2-Aminothiazoles have been synthesized by a one-pot, two-step sequential procedure in solution state which does not involve the isolation of intermediates. It involves α-halogenation of corresponding precursor ketones followed by condensation with substituted thiourea derivatives. All the products were analyzed by IR, NMR, mass spectral techniques and four of them were evaluated crystallographically. One of them crystallizes in the triclinic crystal system with space group  P, while, all the other compounds crystallize in the monoclinic crystal system in two different space groups  viz. P 2 1 /c and  P 2 1 /n. The modified 2-aminothiazole core did not show any change in the intermolecular interaction. The N-H…N interaction predominates over other interactions forming centrosymmetric head to head dimer with the neighboring atoms. This feature is observed in all the molecules except  N -(4-(4-bromophenyl)-3-(2,5-dimethylphenyl)thiazol-2(3 H )-ylidene)-2,5-dimethylaniline.

Sequential One-Pot Synthesis of 2-Aminothiazoles Using Corresponding Ketones: Insights into Their Structural Features