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An eco-safe synthetic route for convenient one-pot synthesizing 1 H -pyrazolo[1,2- b ] phthalazine-5,10-dione derivatives  through  Knoevenagel-Michael cyclocondensation is reported in carboxymethyl cellulose (CMC) based on green chemistry principles. The prominent benefits include use of recyclable green catalyst, commercially accessible inexpensive starting materials, operational simplicity, non-hazardous reaction circumstances, high atom-economy, solvent-free, short reaction times and high yields.

polycyclic aromatic compounds

Carboxymethyl Cellulose (CMC) as a Recyclable Green Catalyst Promoted Eco-Friendly Protocol for the Solvent-Free Synthesis of 1 H -Pyrazolo[1,2- b ]Phthalazine-5,10-Dione Derivatives