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One new lignan, julibrissinoside II, along with thirteen known compounds, was isolated from the stem bark of  Albizia julibrissin . The structure of julibrissinoside II was determined on the basis of extensive spectroscopic methods, including NMR and CD spectroscopic data. The isolated compounds were tested for their SREBP-1c inhibitory activity at different concentrations using mouse hepatocyte AML12 cell lines. Among them, linoleic acid ( 2 ) and 3- O -methylfisetin ( 4 ) showed significant SREBP-1c inhibitory activity at the concentration of 100 µM.

Chemical constituents from the stem bark of Albizia julibrissin and their SREBP-1c inhibitory activity