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Investigation on the chemical components of  Valeriana jatamansi  Jones (Caprifoliaceae), a new lignan with pyran-ring, dipsalignan G ( 1 ), along with eight known compounds ( 2 – 9 ) were isolated. Their structures were elucidated by extensive analysis of 1D, 2D NMR and HR-ESI-MS spectroscopic data. Additionally, possible biosynthetic pathway of  1  was proposed. Finally, biological evaluation results showed that  8  had significant scavenging ability to ABTS and DPPH free radicals, with IC 50  values of 1.35 ± 0.01 and 2.94 ± 0.01 μg/ml, respectively.

Lignans from the root of Valeriana jatamansi and their biological evaluation