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Two new monoterpenoid indole alkaloids 3-hydroxylochnerine ( 1 ) and 10-hydroxyvinorine ( 2 ) were isolated from the roots of  Rauvolfia yunnanensis . Their structures were elucidated based on the analysis of spectroscopic data and ECD calculation. Both compounds exhibited potent antimicrobial activity against  Bacillus subtilis  and  Escherichia coli , and their activities were comparable to the well-known antibacterial drug berberine.

Two new antimicrobial monoterpenoid indole alkaloids from the roots of Rauvolfia yunnanensis