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A new cyclic peptide selapeptin B ( 1 ), together with one known nor-lignan glycoside moellenoside C ( 2 ), was isolated from  Selaginella tamariscina . The structures of  1  and  2  were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS. Two compounds were evaluated for cytotoxic activities against B16F10, MDA-MB-231, and MDA-MB-468 cell lines by MTT assay. Compound  1  showed the potent activity against B16F10 melanoma cell lines.

A new cyclic peptide from Selaginella tamariscina