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Two new isoflavones ( 1  and  2 ), as well as eight known ones were isolated from the roots of  Sophora tonkinensis  Gagnep. Compound  1  represents an unprecedented polymerization pattern constructed by isoflavone and cytisine. Their structures were elucidated by comprehensive spectroscopic data analysis, combined with ECD calculations. Compound  1  displayed significant anti-tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. Moreover, compound  6  exhibited potent  α -glucosidase inhibitory activity with IC 50  value of 47.4 mg/L.

Two new isoflavones from the roots of Sophora tonkinensis