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A new SEK15-derived polyketide compound, strepolyketide D ( 1 ), was isolated from salt-lake-derived  Streptomyces  sp. DBC5, together with two known analogues ( 2-3 ). Their structures were elucidated based on spectroscopic analysis of IR, MS, 1 D and 2 D NMR. Compound  2  elicited moderate antioxidation with IC 50  value of 39.26 μg/ml. The results of the study revealed that salt-lake actinomycetes of Lake Dabancheng appear to have immense potential as a source of polyketide compounds.

Strepolyketide D, a new SEK15-derived polyketide compound from salt-lake-derived Streptomyces sp. DBC5