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Two new dibenzocyclooctane lignans, schisanwilsonins H ( 1 ) and I ( 2 ), together with eight known compounds gomisin J ( 3 ), wulignan A 1  ( 4 ), gomisin S ( 5 ), tigloylgomisin P ( 6 ), gomisin O ( 7 ), (-)-gomisin K 1  ( 8 ), rubschisantherin ( 9 ) and wuweizisu C ( 10 ) were isolated from the 95% ethanol extract of the fruits of  Schisandra wilsoniana .  7  exhibited anti-HBV activity with potency against HBsAg and HBeAg secretion by 37.1% and 32.6%, respectively, at 50 μg/ml.  10  exhibited anti-HIV activity with EC 50  and therapeutic index (TI) values of 2.10 μg/ml and 11.98, respectively.

Schisanwilsonins H and I, two new dibenzocyclooctane lignans from the fruits of Schisandra wilsoniana