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A new megastimane sesquiterpenoid, cassianol A ( 1 ), and five known analogues ( 2–6 ) were isolated from the leaves extract of  Cinnamomum cassia.  Their structures were elucidated by extensive spectroscopic methods and single-crystal X-ray diffraction analyses. All the isolates were isolated from  C. cassia  for the first time. The anti-inflammatory activities of compounds  1–6  were evaluated against nitric oxide (NO) production in LPS-induced RAW 264.7 mouse macrophages.

A new megastimane sesquiterpenoid from the leaves of Cinnamomum cassia