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In this study, the antimicrobial activity and constituents of essential oils from the leaves of  Cinnamomum auricolor  Kosterm. and  C. petelotii  Kosterm collected from Pù Hoạt Natural Reserve (Hạnh Dịch Commune, Quế Phong District), Vietnam were reported. The essential oils obtained by separate hydrodistillation were analyzed by means of gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC-MS). The antimicrobial activities were evaluated by microbroth dilution susceptibility assay. The main constituents of  C. auricolor  comprised of oxygenated sesquiterpenes mainly caryophyllene oxide (26.0%), spathulenol (11.1%), and ( E )-nerolidol (10.7%). However, oxygen-containing monoterpenes were the main compounds identified in  S. petelotii  and they are linalool (34.3%), 1,8-cineole (20.8%) and terpinene-4-ol (9.9%). The essential oil of  C. auricolor  displayed prominent antimicrobial activity towards  Bacillus cereus  ATCC14579 and  Staphylococcus aureus  ATCC25923 with minimum inhibitory concentration (MIC) value of 16.0 μg/mL. In addition, the essential oil of  C. auricolor  also exhibited antimicrobial activity against  Enterococcus faecalis  ATCC29212, and anti-candidal activity towards  Candida albican s ATCC10231 with MIC value of 32.0 μg/mL. The leaf essential oil of  C. petelotii  only exhibited activity towards  S. aureus  and  C. albicans  with MIC value of 64.0 μg/mL. The chemical constituents and antimicrobial activity of both essential oils are being reported for the first time.

journal of essential oil bearing plants

Essential oils of Lauraceae: antimicrobial activity and constituents of  Cinnamomum auricolor  Kosterm. and  Cinnamomum petelotii  Kosterm leaves essential oils from Vietnam