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In this study, the chemical composition, antioxidant potential and antimicrobial interactions with a conventional antibiotic of essential oil (EO) isolated from  Andryala pinnatifida  subsp.  mogadorensis  aerial parts were assessed. Twenty eight compounds were identified. Farnesene (14.92%), Decanal (9.51%) and Tetradecanoic acid (7.44%) were the main compounds. The antibacterial potential was evaluated against two bacterial strains identified as resistant to antibiotics: Methicillin-resistant  Staphylococcus aureus  and  Escherichia coli , as well as two sensitive bacterial strains:  S .  aureus  and  E. coli . The results obtained reveal that no bacterial strain tested was resistant to the studied EO, with MIC values in the range of (1.56-3.12) mg/mL. However, the combination of the studied EO with gentamicin showed a complete synergism against  S. aureus . Furthermore, EO was screened for its antioxidant activity using three methods. IC 50  values were 4.34 ± 0.06 mg/mL, 1.16 ± 0.1 mg/mL and 1.94 ± 0.09 mg/mL, respectively, for DPPH, Ferric reducing and β-carotene/linoleic acid assays. The data indicate that the essential oil of this Moroccan endemic plant proved to be an important source of antioxidant and antibacterial products and may be used for the treatment of pathogenic bacteria and could be also implicated in food industries as preservative of foodstuffs.

journal of essential oil bearing plants

Essential Oil from Aerial Parts of  Andryala pinnatifida  subsp.  mogadorensis : Chemical Composition, Antioxidant and Aantimicrobial Synergistic Effect Against Multidrug-Resistant Bacteria