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Substance use behaviours have been found to cluster in youth, and cannabis use has been previously linked to tobacco and e-cigarette use. The objective of the current study was to examine the bidirectional associations between cannabis, e-cigarette, and cigarette use among a large sample of Canadian secondary school students. A sample of students in grades 9–11 ( n  = 14,652) from Ontario and Alberta, Canada who participated in two waves of the COMPASS Study (Time 1 (T1): 2015–2016; Time 2 (T2): 2016–2017) was identified. Autoregressive cross-lagged models investigated the stability of product use between T1 and T2, as well as the bidirectional associations between current cannabis, e-cigarette, and cigarette use while controlling for demographic covariates. Significant autoregressive and bidirectional associations between all three substances were observed. Students who reported using cigarettes and e-cigarettes at T1 were more likely to report using cannabis at T2. Similarly, students who reported using cannabis at T1 were more likely to report using cigarettes and e-cigarettes at T2. Given the bidirectional associations identified between cannabis, e-cigarette, and cigarette use in this research, continued monitoring of evolving policies related to cannabis and e-cigarette use in Canada is needed. Additionally, school and community-based prevention efforts targeting youth should consider addressing poly-substance use.

Bidirectional associations between cannabis, e-cigarette, and cigarette use among Canadian youth: findings from the COMPASS Study