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To explore the construct validity and reliability of the Greek version of the Interaction with Disabled Persons Scale (IDPS) amongst healthcare students. Greek IDPS factors were extracted and confirmed by Analysis of Moment Structures. Measurement invariance for the group of students completing a clinical module with people with disabilities was also evaluated. The scale was distributed twice, 3 weeks apart (test-retest reliability) to sample. Greek IDPS scores amongst students with frequent contact with people with disabilities were compared with those with infrequent contact (discriminant validity). 327 healthcare students (21.25 ± 4.3 years, 118 males) participated. Exploratory factor analysis extracted 6 factors explaining 55.66% of total variance. Confirmatory factor analysis showed a good fit of the model (AGFI = 0.95 &gt; 0.90, RMSEA = 0.07 &lt; 0.08, CFI = 0.95 ≥ 0.90, SRMR = 0.00 &lt; 0.08). An adequate fit for the students completing a clinical practice module was observed. The scale’s test-retest reliability and internal consistency were excellent; ICC (2,1) =0.86 (CIs:0.82–0.89) and Cronbach’s  α =  0.87, respectively. Statistically significant differences between the two student groups were yielded; students with frequent contact with people with disabilities had lower scores (mean difference: −4.5; CI: −6.6 to −2.4), suggesting that they were significantly more comfortable with people with disabilities than the students with infrequent contact. The Greek IDPS provided sufficient validity and reliability evidence for evaluating healthcare students’ perceptions and attitudes towards people with disabilities.IMPLICATIONS FOR REHABILITATIONThe Greek IDPS demonstrated sufficient validity and reliability evidence to assess the Greek-speaking healthcare students’ perceptions and attitudes towards people with disabilitiesCompleting a clinical module working with people with disabilities is not enough to produce adequately positive attitudes in Greek-speaking undergraduate healthcare students. Therefore, faculties need to organize further actions, such as lectures by people with disabilities, students’ role play, and discussions or events in co-operation with people with disabilities. The Greek IDPS demonstrated sufficient validity and reliability evidence to assess the Greek-speaking healthcare students’ perceptions and attitudes towards people with disabilities Completing a clinical module working with people with disabilities is not enough to produce adequately positive attitudes in Greek-speaking undergraduate healthcare students. Therefore, faculties need to organize further actions, such as lectures by people with disabilities, students’ role play, and discussions or events in co-operation with people with disabilities.

disability and rehabilitation

The Interaction with Disabled Persons Scale: evidencing construct validity with factor analysis and measurement invariance in Greek-speaking healthcare students