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This study of people newly diagnosed of living with HIV (ND-PLHIV) calculated the use, cost and outcome of HIV services at a London HIV centre. ND-PLHIV were followed July 2017-October 2018. Hospital data included inpatient days (IP), outpatient (OP), dayward (DW) visits, tests and procedures, and anti-retroviral drugs (ARVs). Community services were recorded in daily diaries. Mean per patient-year (MPPY) use was multiplied by unit costs. 13.6 MPPY (95%CI 12.4–14.9) OP visits, 0.4 MPPY (95%CI 0.1–0.7) IP days, 0.09 MPPY (95%CI 0.01–0.2) DW visits and 4.6 MPPY community services (95%CI 3.4–5.8). Total annual costs per patient-year (CPPY) was £11,483 (95%CI £10,369–12,597): ARVs comprised 63% and community services 2%. White participants used fewer hospital and more community services compared with minority ethnic community (MEC) participants. Costs for White ND-PLHIV was £10,778 CPPY (95%CI £9629–11,928); £13,214 (95%CI £10,656–15,772) for MEC ND-PLHIV ( p  &lt; 0.06). Annual costs were inversely related to CD4 count at entry ( r  = −5.58,  p  = 0.02); mean CD4 count was 476 cells/mm 3  (95%CI 422–531) versus 373 cells/mm 3  (95%CI 320–425) for White and MEC participants respectively ( p  = 0.03). Annual costs for ND-PLHIV with CD4 ≤ 350 cells/mm 3  was £2478 PPY higher compared with CD4 count &gt;350 cells/mm 3  ( p  = 0.04).

Hospital and community care costs for people newly diagnosed of living with HIV in London, UK