English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

This cohort study evaluated non-adherence to antiretrovirals at referral services in Pernambuco, Brazil, 2016/2017, through self-report. A generalized mixed-effects model for binary outcomewas used. We assessed 542 participants with an adherence rate of 85.50%. A greater chance of non-adherence was associated with:a low/moderate level of nicotine dependence (OR = 2.79,  p  = 0.00, IC = 1.44-5.41); ≥7 tablets/day (OR = 6.14,  p  = 0.00, IC = 3.42-11.02); LPV/r (OR = 1.49,  p  = 0.6, IC = 0.98-2.26), ddI (OR = 3.34,  p  = 0.03, IC = 1.12-9.97), ABC (OR = 4.02,  p  = 0.05, IC = 1.01-16.03), RAL (OR = 2.49,  p  = 0.01, IC = 1.32-4.70) and DTG (OR = 4.65,  p  = 0.01, IC = 1.42-15.16); 6–10 year seropositive diagnosis (OR = 2.17,  p  = 0.01, IC = 1.20-3.92) and symptoms of depression (OR = 1.55,  p  = 0.03, IC = 1.03-2.33). Protective factors for non-adherence weres: ≥50 years (OR = 0.67,  p  = 0.06, IC = 0.45-1.01), secondary/higher education (OR = 0.48,  p  = 0.00, IC = 0.34-0.70), embarrassment at health service (OR = 0.49,  p  = 0.04, IC = 0.24-0.97), good understanding of antiretrovirals (OR = 0.62,  p  = 0.03, IC = 0.40-0.96), adverse event (OR = 0.74,  p  = 0,06, IC = 0.54-1.01), use of TDF (OR = 0.62,  p  = 0.01, IC = 0.43-0.90), NVP (OR = 0.41,  p  = 0.05, IC = 0.71-1.00) and EFZ (OR = 0.48,  p  = 0.01, IC = 0.29-0.80) and good knowledge of HIV/AIDS/ART. (OR = 0.67,  p  = 0.07, IC = 0.43-1.04). Variables with stronger association were those linked to ART. Systematic use of self-report adherence is recommended for priority groups.

Adherence to antiretroviral therapy and factors associated with non-adherence: a cohort study at two referral services in Brazil