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Public health is the most recent of the biomedical sciences to embrace “precision.” Advocates for “precision public health” (PPH) call for a data-driven, computa¬tional approach to public health, leveraging genomic and other data to inform public health decision-making. Yet, like precision medicine, PPH risks overselling the value of genomic data to deter¬mine health outcomes, but on a population level. History has shown that over-emphasizing heredity tends to disproportion¬ately harm underserved minorities and disadvantaged communities. Comparing and contrasting cur¬rent PPH with an earlier attempt at using genetics to inform pub¬lic health during the Progressive era (1890–1920) highlights some potential risks of genotype-driven preventive public health.

Precision Medicine for the Population—The Hope and Hype of Public Health Genomics