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To investigate the pupillary diameter and pupillary light response in patients who have recovered from the COVID-19. Thirty two eyes of 32 patients with a history of COVID-19 in the last two months and 32 eyes of 32 age and sex-matched healthy controls were included in this prospective study. All patients had neurological symptoms. Dynamic and static pupillometry measurements were performed with the Sirius (CSO, Italy) corneal topography device. Patients with COVID-19 had higher mean scotopic, mesopic, and photopic pupil diameters compared to the controls ( p  = .01,  p  = .04,  p  = .02, respectively). In dynamic pupillometry analysis, 0 th , 2 th , 8 th  and 16 th  second pupil diameter measurements were higher in COVID-19 patients ( p  = .02,  p  = .04,  p  = .04,  p  = .04, respectively). There were no differences in the average speed of pupillary dilatation ( p  &gt; .05). Our findings suggest that the pupillary response, an indicator of autonomic nervous system activity, may be affected in COVID-19 patients with neurological symptoms.

Evaluation of Pupillometric Parameters in Patients with COVID-19