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to study the clinical features of uveitis-glaucoma-hyphema (UGH) syndrome, particularly those useful for a differential diagnosis from unilateral hypertensive acute anterior uveitis. A retrospective chart review was conducted on the clinical features of 9 patients with UGH syndrome. These features were then compared with those detected in 50 patients with unilateral hypertensive acute anterior uveitis. Fine and pigmented keratic precipitates ( p  = .0002 and  p  = .00004, respectively), iris atrophy ( p  = .0122), hyphema and vitreous opacities &gt; 2+ ( p  = .0003), and cystoid macular edema ( p  = .009) were statistically associated with UGH syndrome. These clinical signs show a high specificity, ranging from 58 to 100%; the presence of pigmented keratic precipitates in the setting of a unilateral acute hypertensive anterior uveitis has a sensitivity and specificity of 89% and 84%, respectively. In patients operated on for cataract, UGH syndrome can be differentiated from unilateral hypertensive acute anterior uveitis considering specific clinical signs.

Uveitis-Glaucoma-Hyphema Syndrome: Clinical Features and Differential Diagnosis