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We aim to describe ocular infection epidemiology for a public tertiary care hospital in New York City (NYC). We retrospectively reviewed 558 patients with ocular isolates from conjunctival, corneal, and intraocular culture from 2009 to 2017 for microbial growth and antimicrobial sensitivities. In total, 185 ocular cultures (33%) had growth and the most commonly isolated microbes overall were  Staphylococcus aureus (S. aureus)  (23%), coagulase-negative Staphylococcus (CoNS) (23%),  Pseudomonas aeruginos a  (P. aeruginosa)  (16%),  and Streptococcus viridans (S. viridans)  group (11%). The most common microbes within corneal (n = 61), conjunctival (n = 34), and intraocular isolates (n = 9) were  P. aeruginosa  (37.7%),  S. aureus  (35.3%), and  S. viridans  group (33.3%), respectively. Proportion of isolates exhibiting multi-drug resistance decreased over time ( P  = .006). The microbial epidemiology of ocular infection of a public NYC hospital was distinct from other geographic locations, underscoring the importance of examining local profiles to more precisely inform empiric therapy.

Common Microbes and Antibiotic Resistance in Ocular Infections at an Urban Public Tertiary Care Hospital