Open AccessAbsorption of bovine angiogenin into peripheral blood of rats orally administered milk basic protein
Author(s) -
Yuko Ishida,
Takehiko Yasueda,
Hiroki Murakami,
Ken Kato
Publication year - 2016
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1080/09168451.2016.1246176
Subject(s) - angiogenin , resorption , bovine milk , peripheral blood , oral administration , absorption (acoustics) , chemistry , bone resorption , pharmacology , bovine serum albumin , medicine , endocrinology , chromatography , angiogenesis , acoustics , physics
Bovine angiogenin is a major component of the bone resorption inhibitory activity of milk basic protein (MBP). The intestinal absorption of bovine angiogenin was investigated in a rat model, where it was detected in an intact form in the peripheral blood after the oral administration of MBP. This finding demonstrates that orally administered bovine angiogenin is absorbed without being degraded.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom