English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The aim of this current study was to identify the prevalence and risk factors of  H. pylori  infection in the low-risk area of gastric cancer in China, and evaluate the value of different gastric cancer screening methods. An epidemiological study was conducted in Yudu County, Jiangxi, China, and participants were followed up for 6 years. All participants completed a questionnaire, laboratory tests and endoscopy. Patients were divided into  H. pylori  positive and negative groups, and risk factors for  H. pylori  infection were identified using multivariate logistic regression analysis. A total of 1962 residents were included, the prevalence of  H. pylori  infection was 33.8%. Multivariate analysis showed that annual income ≤20,000 yuan (OR: 1.44, 95% CI: 1.18–1.77,  p  &lt; 0.001), loss of appetite (OR: 1.71, 95% CI: 1.29-2.26,  p  &lt; 0.001), PG II &gt;37.23 ng/mL (OR: 2.11, 95% CI: 1.50–2.97,  p  &lt; 0.001), G-17 &gt; 1.5 and ≤5.7 pmol/L (OR: 2.52, 95% CI: 1.93–3.30,  p  &lt; 0.001), and G-17 &gt; 5.7 pmol/L (OR: 1.96, 95% CI: 1.48–2.60,  p  &lt; 0.001) were risk factors of  H. pylori  infection, while alcohol consumption (OR: 0.70, 95% CI: 0.54–0.91,  p  = 0.006) was a protective factor. According to the new gastric cancer screening method, the prevalence of low-grade intraepithelial neoplasia in the low-risk group, medium-risk group and high-risk group was 4.4%, 7.7% and 12.5% respectively ( p  &lt; 0.001). In a low-risk area of gastric cancer in China, the infection rate of  H. pylori  is relatively low. Low income, loss of appetite, high PG II, and high G-17 were risk factors for  H. pylori  infection, while alcohol consumption was a protective factor. Moreover, the new gastric cancer screening method better predicted low-grade intraepithelial neoplasia than the ABC method and the new ABC method.

annals of medicine

Investigation of the prevalence and risk factors of  Helicobacter pylori  infection and the value of different gastric cancer screening methods in a low-risk region of gastric cancer in China