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A framework for Computer-Aided Diagnosis (CAD) to diagnose Cavitary TB and Miliary TB from chest Computed Tomography (CT) slices has been designed and implemented. The lung tissues from the CT slices are segmented using region-based Active Contour Model (ACM) and the Region of Interests (ROIs) labelled by an expert radiologist are extracted. Features based on shape and texture are extracted from each ROI. A wrapper-based Improved Artificial Bee Colony Optimization (I-ABCO) algorithm with the accuracy of the Support Vector Machine (SVM) classifier as the fitness function is used to select the optimal subset of features. The search process of I-ABCO is improved using two evaluation functions, namely, rough dependency measure (RDM) and mutual information (MI), to promote better exploitation of the search space. The selected features are used to train the Radial Basis Function Neural Network (RBFNN) classifier, using ten-fold cross validation and the performance is evaluated. Experimentation has been performed on CT slices using two datasets: Tuberculosis dataset and Lung Image Database Consortium-Image Database Resource Initiative (LIDC-IDRI) dataset. The accuracy of the CAD systems using I-ABCO with MI and I-ABCO with RDM for both datasets are (88.34%, 92.63%) and (87.32%, 90.17%), respectively. The CAD system using the basic Artificial Bee Colony Optimization (ABCO) algorithm for feature selection is also experimented with the same datasets and an accuracy of (85.68%, 88%) is achieved. The performance of the proposed algorithms outperforms the ABCO algorithm in diagnostic accuracy, which ensures that selecting the optimal feature subset efficiently has an impact on the classification accuracy.

Computer-Aided Diagnosis System for Diagnosis of Cavitary and Miliary Tuberculosis Using Improved Artificial Bee Colony Optimization