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In this paper, a novel way of choosing the initial estimates for solving magnetocardiographic inverse problems using the pattern search method is reported. As opposed to the conventional choice of pseudo random numbers, the co-ordinates of the maximum spatial gradient of magnetic fields across sensor locations were used as initial estimates for pattern search method with the help of current density maps. The proposed method has been extensively validated by computer simulation and test coil localization before applying to real magnetocardiogram of a few healthy subjects and those with a known conduction anomaly and ischemic heart disease.

Solving Inverse Problem in Magnetocardiography by Pattern Search Method