English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

In this work, we present a fast, simple and selective method for the extraction/preconcentration and determination of five opium alkaloids. This method is based on the combination of dispersive solid phase extraction with magnetic molecularly imprinted polymers (MMIP) and determination via high performance liquid chromatography. The surface modified Fe 3 O 4  nanoparticles were synthesised in-situ, from a co-precipitation method by addition of a mixture of the methacrylic acid and ammonia to a mixture of Fe 2+ /Fe 3+  under nitrogen atmosphere. MMIP was prepared from surface modified nanoparticles in the presence of ethylene glycol dimethyl acrylate as cross-linker and azobisisobutyronitrile as initiator and template molecule under reflux in acetonitrile. MMIPs for five natural occurring opium alkaloids, including morphine (MO), codeine (CO), thebaine (TE), noscapine (NO) and papaverine (PA) were prepared in the same manner. Structural characterisation and elucidation of both synthesised nanoprticles were performed by Fourier transform-infrared spectroscopy, scanning electron microscopy. X-ray diffraction and vibrating sample magnetometry. A precise chromatographic method was developed and coupled with extraction with MMIP nanoparticles for simultaneous preconcentration and determination of above-mentioned alkaloids in underground water samples. The limit of detection obtained 0.007, 0.007, 0.004, 0.003, 0.003 mg L −1  for MO, CO, TE, NO and PA, respectively and recoveries were about 97–102%. Linear dynamic range and relative standard deviation were 0.03–100 mg L −1  and less than 1.5% for each analyte.

international journal of environmental analytical chemistry

Simultaneous determination of five opium alkaloids in underground waters using molecularly imprinted polymer-modified magnetic nanoparticle based dispersive micro-solid phase extraction followed by high performance liquid chromatography