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The purpose of the present study was to examine tests of interaction effects between cannabis protective behavioral strategies use and a range of risk/protective factors for negative cannabis-related consequences. We recruited 2,226 college students ( M age = 20.28,  SD  = 3.37; 68.8% female; 75.4% White) from 10 universities throughout the U.S. who reported using cannabis in the past month to complete an online survey. Measures assessed cannabis use, negative cannabis-related consequences, cannabis protective behavioral strategies use, and 35 risk/protective factors (including socio-demographic characteristics). Cannabis protective behavioral strategies use was negatively correlated with negative cannabis-related consequences while including the risk/protective factors as covariates. Most importantly, 33% and 54% of the interaction effects tested were statistically significant, depending on the covariates entered into the model. The interaction effects had a consistent pattern such that the positive association between greater risk and negative cannabis-related consequences was weaker as cannabis protective behavioral strategies use increased. Findings suggest that the nature of these interaction effects is not specific for any given risk/protective factor. We draw parallels to research on alcohol protective behavioral strategies and offer suggestions for moving the cannabis protective behavioral strategies field forward.

A Test of Interaction Effects Between Cannabis Protective Behavioral Strategies and Antecedents of Cannabis-Related Consequences