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This study evaluated caregivers’ stress and depressive symptoms, and children’s asthma control, before COVID-19 began and after its onset among families in the RVA Breathes program. The RVA Breathes intervention, which took place in an urban city in the United States, includes asthma education delivered by a community health worker (CHW), a home assessment, and school nurse components. Participants included 125 children (5–11 years) with asthma and their caregivers (48% household income &lt;$25,000) enrolled prior to the pandemic. Families were randomized to an active intervention arm (full intervention or intervention without school nurse component) or the control group. Caregivers completed the Center for Epidemiological Studies Depression Scale (CES-D) and the Perceived Stress Scale (PSS); children and caregivers completed the Childhood Asthma Control Test (cACT). Assessments pre-COVID-19 were compared to those completed after the pandemic’s onset. Children in both intervention groups had better cACT scores after the start of COVID-19 compared to before ( t (55) = −2.131,  p  = .019;  t (28) = −2.893,  p  = .004). Caregivers in the intervention groups had lower PSS scores after the start of COVID-19 compared to pre-COVID-19 ( t (53) = 3.928,  p  &lt; .001;  t (28) = 2.568,  p  = .008). Furthermore, CES-D scores improved among caregivers in the full intervention ( t (48) = 1.789,  p  = .040). Caregivers in the control condition did not report significant changes in stress or depressive symptoms. Findings suggest that support from interventionists, including CHWs, might have alleviated stress and depressive symptoms during COVID-19, as well as improved asthma control during the pandemic.

Changes in caregiver mental health and pediatric asthma control during COVID-19