English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Triple-crossover randomized controlled intervention trial to test whether reduced exposure to household NO 2  or fine particles results in reduced symptoms among children with persistent asthma. Children ( n  = 126) aged 5–11 years with persistent asthma living in homes with gas stoves and levels of NO 2  15 ppb or greater recruited in Connecticut and Massachusetts (2015–2019) participated in an intervention involving three air cleaners configured for: (1) NO 2  reduction:  sham  particle filtration and  real  NO 2  scrubbing; (2) particle filtration: HEPA filter and  sham  NO 2  scrubbing; (3) control:  sham  particle filtration and  sham  NO 2  scrubbing. Air cleaners were randomly assigned for 5-week treatment periods using a three-arm crossover design. Outcome was number of asthma symptom-days during final 14 days of treatment. Treatment effects were assessed using repeated measures, linear mixed models. Measured NO 2  was lower (by 4 ppb,  p  &lt; .0001) for NO 2 -reducing compared to control or particle-reducing treatments. NO 2 -reducing treatment did not reduce asthma morbidity compared to control. In analysis controlling for measured NO 2 , there were 1.8 (95% CI −0.3 to 3.9,  p  = .10) fewer symptom days out of 14 in the particle-reducing treatment compared to control. It remains unknown if using an air cleaner alone can achieve levels of NO 2  reduction large enough to observe reductions in asthma symptoms. We observed that in small, urban homes with gas stoves, modest reductions in asthma symptoms occurred using air cleaners that remove fine particles. An intervention targeting exposures to both NO 2  and fine particles is complicated and further research is warranted. NCT02258893.

Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial