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The lung functions of children with obese asthma seem to be distinct from those of obese children or lean asthmatics. To measure baseline lung function, exercise-induced bronchoconstriction (EIB), and bronchial hyperreactivity (BHR) in school-age obese asthmatics (OA group) and to compare the data with obese children (O group), lean asthmatics (A group), and healthy controls (H group). One hundred seventy school-age children were enrolled in this prospective cross-sectional study. Baseline fractionated exhaled nitric oxide (FeNO), and baseline, post-exercise (post-E), and post-bronchodilation (post-BD) impulse oscillometry (IOS) and spirometry tests were performed. EIB and BHR were evaluated based on the difference (Δ) in post-E - baseline, and post-BD – baseline values. The mean FeNO level was higher in the OA group than in the other groups ( p  = 0.002). Baseline zR5 and R5-20 were higher ( p  = 0.013 and  p  = 0.044), but zFEF25-75 was lower ( p  &lt; 0.01), in the OA group. ΔPost-E – baseline zFEV1 was lower in the A group ( p  = 0.003) but was higher in the OA group ( p  = 0.014) than the other groups. ΔPost-BD – baseline zFEV1 was lower in the H group compared to the other three groups ( p  = 0.004), but no significant difference was observed among the O, A, and OA groups ( p  &gt; 0.05). Higher airway inflammation (high FeNO), peripheral airway resistance (high zR5 and zR5-20) and a lower peripheral airway flow (low FEF25-75) were observed at baseline measurement in school-age obese asthmatics compared to lean asthmatics and obese children. Obese asthmatics had no EIB but exhibited a similar BHR to that of asthmatics.

School-age obese asthmatic children have distinct lung function measures from lean asthmatics and obese children