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Purpose : The purpose of the research was to determine the changes in metabolic parameters, leptin, and irisin levels after aerobic and resistance training in type-2 diabetes obese men.  Methods : Forty-five participants in the age range of 17–25 years were randomized into three groups: aerobic training (AT), resistance training (RT), and control (CO). All training sessions were fulfilled 4 days per week for two months. The aerobic training began with intensity of 65% of the maximum aerobic power and finished with 90%. The resistance program started with 50% of one-repetition maximum and reached 70% in the 8th week.  Results : Factorial analysis of variance and Bonferroni post-hoc test revealed significant decreases in leptin ( p  = .043), fasting blood sugar (FBS) ( p  = .023), insulin ( p  = .001), homeostasis model assessment for insulin resistance (HOMA-IR) ( p  = .022) in AT compared with CO and insulin ( p  = .006) in AT compared with RT. The change of percent body fat (PBF) was positively correlated only with change of HOMA-IR in AT group ( p  = .032) at  p  &lt; .05.  Conclusion : The result suggests that, compared to resistance training, aerobic training can control metabolic situations such as insulin resistance through the leptin hormone function, and not irisin in type-2 diabetes obese men.

Aerobic Versus Resistance Training: Leptin and Metabolic Parameters Improvement in Type 2 Diabetes Obese Men