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Recent declines in life expectancy in the US, especially for middle-aged White persons, have called attention to mortality from deaths of despair – deaths due to alcohol, drugs, and suicide. Using data from the Centers for Disease Control and the U.S. Census Bureau, this paper examined deaths of despair by race/ethnicity, age, cause of death, birth cohort, and sex in Missouri. We focused on Area Agencies on Aging as geographic units of interest to increase usefulness of our findings to public administrators. Deaths of despair began trending up for all age groups beginning in 2007–2009, with the sharpest increases occurring for Black or African American non-Hispanics beginning in 2013–2015. The most dramatic increases occurred for the population age 50–59 in St. Louis City and Area Agency on Aging regions in southern Missouri. For older adults, considerable variation in rates, trends, and cause of deaths of despair is evident across the state.

Deaths of Despair and Population Aging in Missouri