English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The treatment of neurogenic bladder (NB) is a challenge because conventional therapy often fails. Sacral neuromodulation (SNM) is a minimally invasive technique and an unconventional treatment for neurogenic bladder. Its research is still in the exploratory stage. The research on its effectiveness and safety is not clear. To assess the effectiveness and safety of sacral neuromodulation (SNM) for neurogenic bladder (NB). By searching the PubMed databases and Cochrane Library databases, combined with the method of literature tracing, the clinical researches and works on neurogenic bladder and sacral neuromodulation therapy were collected. Two reviewers independently selected and extracted data, (1) determine whether the study meets the inclusion criteria and exclude the literature that meets the exclusion criteria. (2) Researchers’ screening results and data, if there are differences in the results, will be discussed to eliminate the differences. (3) Read the full text of the literature carefully to determine the final literature to be included. (4) The relevant data of 11 independent studies, a total of 291 patients, were systematically reviewed using review manager 5.3 software. This research included 11 independent studies with a total of 291 patients. The improvements of main outcomes before and after SNM therapy were significant: incontinence episodes /24 h (WMD −2.52; 95%CI-3.14-1.90;  p  &lt;0.001), frequency/24 h (WMD-5.96; 95%CI −6.27-5.66;  p  &lt;0.001), voiding volume (WMD 116.09 mL; 95%CI 86.68145.51;  p  &lt;0.001), cystometric capacity (WMD 129.84 mL; 95%CI 100.53, 159.15;  p  &lt;0.001), post-void residual volume (WMD-198.00 mL; 95%CI-264.60, −131.40;  p  &lt;0.001), clean intermittent self-catheterization/24 h (WMD-2.48; 95%CI −2.96, −2.00;  p  &lt;0.001). This systematic review indicated that the sacral neuromodulation treatment for neurogenic bladder was effective and safe.

Effectiveness and safety of sacral neuromodulation for neurogenic bladder