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The use of mobile phone and factors influencing usage have least been explored in spite of its relevance in mHealth adoption. We conducted a descriptive exploratory study to evaluate the use of mobile phone alarm application, text messaging and voice call among HIV positive clients. We randomly selected 362 respondents who were 18–65 years and receive care from two health facilities in Accra, Ghana. Questionnaires were administered and data analysed to describe and predict mobile phone use. SPSS version 20 was used to process data for analysis. Findings revealed respondent ( n  = 338, 93%) did not share their mobile phones. Voice call was predominantly used ( n  = 227, 63%) while text messaging and mobile alarm functions were sparingly used. Majority ( n  = 285, 78.9%) did not use the mobile phone application to support adherence. Age and employment predicted the use of mobile phone alarm (OR ± 1.56,  p  &lt; 0.05), test messaging (OR ± 1.48,  p  &lt; 0.05) and voice calls (OR ± 1.25,  p  &lt; 0.05). We observed that younger age and employment influence the use of mobile phones. Voice calls are more acceptable because it is simple and easy to use. Knowledge and persuasion are fundamental to mobile phone literacy skills development and should be integrated in mHealth interventions.

Use of mobile phone among patients with HIV/AIDS in a low-middle income setting: a descriptive exploratory study