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The aim of this study was to analyse knowledge and attitudes of pregnant women about Coronavirus disease (COVID-19) and its vaccine. Pregnant women who attended outpatient maternal care between October 2020 and March 2021 were invited to participate in this cross-sectional survey study. To identify the effect of baseline characteristics of participants on their vaccination decision, the pregnant women were divided into two groups as accepting or rejecting the COVID-19 vaccine. The Multiparity rate was significantly higher in the rejection group (73.8 vs. 42.3,  p  = .001). Education level and rate of employment in the professional health sector were significantly higher in the acceptance group ( p  = .001 and  p  = .008). A total of 103 (26.4%) pregnant women from the acceptance group, and 23 (10.9%) from the rejection group had a history of the death of relatives and acquaintances from COVID-19 ( p  = .001). The present study demonstrated that nulliparous status, higher education level, working as a professional healthcare provider and incidence of death in relatives due to COVID-19 significantly rise pregnant women’s acceptance of the COVID-19 vaccine. Considering the overall acceptance rate of 65%, improved vaccination programmes using all types of information sources need to be the main task to block the COVID-19 pandemic.IMPACT STATEMENTWhat is already known on this subject?  There are previous studies that evaluated the attitudes and beliefs about several vaccine types among pregnant women. An important part of tackling the COVID-19 pandemic is the success of the COVID-19 vaccination program in pregnant women. In this respect, it is important to know the attitudes of pregnant women regarding COVID-19 vaccination.What do the results of this study add?  The baseline characteristics of pregnant women with or without acceptance of COVID-19 vaccination were similar regarding COVID-19 infection. The rates of being not multiparous and a health worker were higher in women with acceptance of COVID-19 vaccination. The rate of loss of relatives was also higher in women with acceptance of COVID-19 vaccination. In women without acceptance of COVID-19 vaccination, the major drawback was related to the possibility of harm to their baby’s and own health.What are the implications of these findings for clinical practice and/or further research?  In pregnant women, the attitude to COVID-19 vaccination may be modifiable by the design of focussed information media with respect to their education, occupation, and parity. Longitudinal studies are needed to determine whether this approach can effectively increase the rate of COVID-19 vaccination in pregnant women. What is already known on this subject?  There are previous studies that evaluated the attitudes and beliefs about several vaccine types among pregnant women. An important part of tackling the COVID-19 pandemic is the success of the COVID-19 vaccination program in pregnant women. In this respect, it is important to know the attitudes of pregnant women regarding COVID-19 vaccination. What do the results of this study add?  The baseline characteristics of pregnant women with or without acceptance of COVID-19 vaccination were similar regarding COVID-19 infection. The rates of being not multiparous and a health worker were higher in women with acceptance of COVID-19 vaccination. The rate of loss of relatives was also higher in women with acceptance of COVID-19 vaccination. In women without acceptance of COVID-19 vaccination, the major drawback was related to the possibility of harm to their baby’s and own health. What are the implications of these findings for clinical practice and/or further research?  In pregnant women, the attitude to COVID-19 vaccination may be modifiable by the design of focussed information media with respect to their education, occupation, and parity. Longitudinal studies are needed to determine whether this approach can effectively increase the rate of COVID-19 vaccination in pregnant women.

Assessment of factors affecting attitudes and knowledge of pregnant women about COVID-19 vaccination