English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Poly(ɛ-caprolactone)-silver nanocomposite were prepared by two main methods of metal-polymer nanocomposite preparation approaches,  in situ  and  ex situ  methods, by electrospinning. Effective parameters on electrospun nanofibers were optimized by Design Expert, CCD method. Using  in situ  and  ex situ  methods, effect of incorporating silver nanoparticle into Poly(ɛ-caprolactone) on conductivity, average fiber diameter, morphology of nanofiber mats and antibacterial properties were investigated. According to Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive X-ray Spectroscopy (EDX) analysis, average fibers diameters decreased by increasing incorporated Ag nanoparticles. Conductivity results confirmed the higher content of silver nanoparticles in  in situ  samples. Antibacterial test was performed against two bacteria types:  Staphylococcus-aureus  and  Escherichia-coli . Due to higher content and smaller size of Ag nanoparticles incorporated in nanofibers, silver-loaded PCL electrospun nanofibers obtained by  in situ  method showed higher antibacterial efficiency in comparison to the  ex situ  samples. Moreover, Ag particles had more effects on  Staphylococcus aureus  due to sensitive membrane of this type of bacteria. In vivo study has proved that  in situ  samples improved the wounds on Wistar rat lateral part of body skin. Antibacterial and in vivo results showed that PCL-Ag nanofiber mats obtained by  in situ  method are suitable for medical applications.

Antibacterial and in vivo studies of poly(ɛ-caprolactone)-silver electrospun nanofibers: effect of preparation methods on the properties