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In the few decades, tissue engineering has been a compelling emerging technology that is expected to impact the fields of diagnostics, therapeutic sciences, and the prevention of diseases in a fundamental way. Most of the current research has been focused on optimizing the biomechanical and physicochemical properties of nanomaterials to induce regeneration. However, the clear benefits of tissue engineering are often confronted by concerns about the lack of adequate information regarding their interactions with the immune system. The present manuscript explores such properties and interactions in materials used in craniofacial tissue regeneration.

The immune system and its response to polymeric materials used for craniofacial regeneration