English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The synthesis of novel thiazolidinone derivatives  via  the three-component reaction has been developed involving the reaction of thiosemicarbazide with maleimide and Meldrum’s acid in a single pot. Optimization of reaction conditions was studied with different solvents and quantities of raw materials. The optimum results were obtained when the reaction was carried out in the ratio (2:2:1 mmol) of maleimide, thiosemicarbazide, and Meldrum’s acid, in the presence of two drops of triethylamine in ethanol. The products were formed with good yields with a significant decrease in reaction time. The structures of thiazolidinones were elucidated by  1 H,  13 C NMR, FT-IR spectroscopy, HRMS, and X-ray diffraction.

Synthesis of novel 4-thiazolidinone derivatives via one-pot three-component reaction of maleimide, thiosemicarbazide, and Meldrum’s acid