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Colon Capsule Cleansing Assessment and Report (CC-CLEAR) is a novel quantitative bowel preparation scale for colon capsule. The aim of this study is to validate the association between CC-CLEAR’s classification and major CC outcomes: lesion detection rate, surveillance recommendations and post-CC endoscopic treatment. Multicentric cohort of consecutive CCs. An expert’s panel decided post-CC recommendations. Data included CC-CLEAR and Leighton-REX scales. Major CC outcomes were associated with the different cleansing grades. From 168 CC’s included, findings were reported in 123 (73.2%), 67 (54.4%) of those being colorectal polyps. CC-CLEAR influenced CC’s lesion detection (OR 1.25 95% IC [1.07–1.46],  p -value .004) and polyp detection rate (OR 1.22 95% IC [1.04–1.43],  p -value.014). Thirty-two (19%) post-CC colonoscopies were recommended, including 22 (68.75%) with at least one polypectomy. CC-CLEAR was associated with post-CC colonoscopy treatment (OR 1.40 95% IC [1.07–1.84],  p -value .015). Regarding surveillance, CC-CLEAR influenced the decision for immediate CC repetition (OR 0.21 95% IC [0.12–0.36],  p -value &lt; .001) and the recommendation for CC in 3–5 years’ time (OR 1.47 95% IC [1.50–1.86],  p -value &lt; .002). The Leighton–Rex scale was not correlated with major CC outcomes. CC-CLEAR impacts major CC outcomes: lesion detection, surveillance recommendations and post-CC endoscopic treatment.

scandinavian journal of gastroenterology

CC-CLEAR (Colon Capsule Cleansing Assessment and Report): the novel scale to evaluate the clinical impact of bowel preparation in capsule colonoscopy – a multicentric validation study