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Surface modification of titanium (Ti) implants to meet both antibacterial and biocompatibility requirements is of prime significance since it can almost guarantee implantation success. This contribution attempts to modify the surface of Ti by an integrated three-step treatment, including chemical etching, silanisation, and deposition of a silver nanoparticles (Ag NPs)-containing layer. The morphological characteristics, antibacterial activity, and biocompatibility of the modified Ti were evaluated as a function of etching time, silanisation time, and solvent type. The results illustrated the importance of the surface modification parameters in attaining favourable antibacterial performance and biocompatibility. The Ag-coated Ti substrate which underwent 2  h etching followed by 2  h silanisation in an ethanol solvent suggested the highest antibacterial activity and biocompatibility. It is believed that the application of an appropriate surface modification approach allows new ways to produce Ti implants for medical applications.

Antibacterial activity and biocompatibility of Ag-coated Ti implants: importance of surface modification parameters