Open AccessBiological clocks
Author(s) -
Norio Ishida,
Maki Kaneko,
Ravi Allada
Publication year - 1999
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.96.16.8819
Subject(s) - circadian rhythm , bacterial circadian rhythms , biology , chronobiology , circadian clock , clock , rhythm , gene , mechanism (biology) , neuroscience , computational biology , evolutionary biology , genetics , medicine , epistemology , philosophy
Circadian rhythms describe biological phenomena that oscillate with an approximately 24-hour cycle. These rhythms include blood pressure, body temperature, hormone levels, the number of immune cells in blood, and the sleep-wake cycle. In this paper, we will focus on common genes between species that are responsible for determining the circadian behavior, especially some transcription factors (i.e., switch genes) that serve to regulate many circadian rhythm genes. The intent of this summary is to introduce the common molecular mechanism of biological clocks between flies and humans and then to describe the research from three laboratories that was presented in the session.
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