Open AccessA Tumor-Associated Antigen in Human Nephroblastomas
Author(s) -
P Burtin,
MarieClaude Gendron
Publication year - 1973
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.70.7.2051
Subject(s) - wilms' tumor , antigen , carcinoembryonic antigen , antiserum , biology , virology , immunology , microbiology and biotechnology , cancer , genetics
Antisera prepared against extracts of human nephroblastomas (Wilms' tumors) allowed the characterization in these extracts, and in a few extracts of tumors of other organs, of a tumor-associated antigen. This antigen is different from all previously described antigens, and was named W antigen (W for Wilms). It does not seem to be a carcinoembryonic antigen, and hence it could be of viral origin.